TABLE 2.

HBs, diphtheria, tetanus, polio, and pertussis immune responses 1 month after primary vaccination

AntibodyAssay cutoffGroup
MenC (n = 90)MenCads (n = 99)Hib10-MenC10 (n = 94)Hib5-MenC5 (n = 95)Control (n = 105)
% of subjects respondingGMC/Ta% of subjects respondingGMC/T% of subjects respondingGMC/T% of subjects respondingGMC/T% of subjects respondingGMC/T
HBs10 mIU/ml96.6325.198.0373.493.3318.397.9344.698.0354.0
Diphtheria0.1 IU/ml98.91.68*100.01.77*100.01.66*100.01.78*100.03.17
Tetanus0.1 IU/ml100.02.97*100.03.32*100.02.66*100.03.19*100.01.99
PT5 ELISA units/ml100.056.5100.061.5100.057.2100.062.8100.058.7
VRb97.797.996.6100.098
FHA5 ELISA units/ml100.0230.2100.0237.3100.0221.6100.0245.5100.0211.7
VR100.0100.097.8100.097.0
PRN5 ELISA units/ml98.9135.8100.0148.4100.0133.0100.0136.399.0134.0
VR97.799.097.7100.099.0
Polio 11:898.6230.6100.0318.1100.0217.7100.0252.7100.0281.6
Polio 21:897.1147.9100.0191.798.7154.098.7167.298.9138.9
Polio 31:8100.0394.3100.0531.6100.0484.8100.0507.8100.0530.4
  • a Asterisks indicate statistically significant differences relative to the control group.

  • b VR, vaccine response (postvaccination antibody concentration greater than or equal to the assay cutoff value for initially seronegative infants and the prevaccination concentration in initially seronegative infants).