TABLE 2.

VetTB STAT-PAK test responses in cattle infected with M. bovis by aerosol or intratonsillar inoculationa

RouteWk after inoculationResponder rate (no. of positive/total no. inoculated)
Aerosolb−10/9
48/9
8.58/9
178/9f
Intratonsillarc−10/8
70/8
103/8f
160/8f
188/8f
Intratracheald00/6
20/6
55/6
93/6
134/6
166/6f
Intranasale00/2
32/2
62/2
122/2
  • a The VetTB STAT-PAK test utilizes a unique cocktail of several recombinant antigens, including MPB83, ESAT-6, and CFP-10, optimized by evaluation of antigen recognition patterns using MAPIA.

  • b Cattle received 105 CFU of M. bovis (either strain 95-1315 [n = 5] or HC2005T [n = 4]) by the aerosol route.

  • c Cattle received 4 × 104 CFU of M. bovis strain 95-1315 by instillation directly into the tonsillar crypts.

  • d Cattle received 4 × 104 CFU of M. bovis strain T/91/1378 via intratracheal administration.

  • e Cattle received 106 CFU of M. bovis strain AF2122/97 via intranasal administration.

  • f After skin test.