TABLE 2.

Population expression frequency of DRB1/DQB1 haplotypes and comparison by HIV statusa

DRB1-DQB1 haplotype expressedPopulation frequencyb (95% confidence interval)No. (%) of individuals with the indicated allele groupsP valuec
HIV+ (n = 74)HIV (n = 55)
DRB1*01-DQB1*035.9 (2.5, 13.3)0 (0.0)5 (9.1)0.013
DRB1*01-DQB1*047.5 (3.6, 15.2)1 (1.4)6 (10.9)0.042
DRB1*01-DQB1*057.3 (3.5, 14.5)3 (4.1)5 (9.1)0.28
DRB1*01-DQB1*065.4 (2.4, 11.7)4 (5.4)3 (5.5)1.00
DRB1*03-DQB1*0418.0 (11.8, 26.4)13 (17.6)10 (18.2)1.00
DRB1*03-DQB1*065.7 (2.8, 11.3)7 (9.5)2 (3.6)0.30
DRB1*04-DQB1*0311.8 (7.0, 19.3)10 (13.5)6 (10.9)0.79
DRB1*07-DQB1*028.0 (4.2, 14.8)7 (9.5)4 (7.3)0.76
DRB1*08-DQB1*039.0 (4.7, 16.5)4 (5.4)6 (10.9)0.32
DRB1*08-DQB1*046.4 (3.1, 12.6)6 (8.1)3 (5.5)0.73
DRB1*10-DQB1*055.7 (2.4, 12.5)2 (2.7)4 (7.3)0.40
DRB1*11-DQB1*0324.4 (17.2, 33.3)19 (25.7)13 (23.6)0.84
DRB1*11-DQB1*055.0 (2.1, 11.3)3 (4.1)3 (5.5)0.70
DRB1*11-DQB1*0619.1 (12.5, 28.1)8 (10.8)13 (23.6)0.058
DRB1*12-DQB1*055.0 (2.1, 11.3)3 (4.1)3 (5.5)0.70
DRB1*12-DQB1*066.4 (3.1, 12.6)6 (8.1)3 (5.5)0.73
DRB1*13-DQB1*037.4 (3.9, 13.6)8 (10.8)3 (5.5)0.35
DRB1*13-DQB1*045.0 (2.5, 9.9)8 (10.8)1 (1.8)0.077
DRB1*13-DQB1*058.7 (4.6, 15.9)6 (8.1)5 (9.1)1.00
DRB1*13-DQB1*0622.4 (15.5, 31.4)15 (20.3)13 (23.6)0.67
DRB1*15-DQB1*037.3 (3.5, 14.5)3 (4.1)5 (9.1)0.28
DRB1*15-DQB1*0619.4 (12.8, 28.2)11 (14.9)12 (21.8)0.36
  • a Heterozygous expression at DRB1 was found for 86.3% of individuals, so these individuals may contribute twice to these frequencies. For example, if an individual expresses DRB1*01/03 and DQB1*05, that individual contributes to the DRB1*01-DQB1*05 and DRB1*03-DQB1*05 haplotype frequencies.

  • b Expressed as a percentage.

  • c Significant values are boldfaced.