TABLE 3.

Diagnostic accuracy of vaccination history and TQS test in the emergency department and in the laboratory, with ELISA as reference

TestPro- tectedaNot pro- tectedaLikelihood ratio (95% CI)
Structured clinical history
    Complete and certain vaccination575112.99 (1.77-5.09)
    Incomplete vaccination8890.56 (0.30-1.05)
    Dubious or no vaccination250310.46 (0.36-0.59)
    Unknown vaccination history1120.31 (0.07-1.39)
    Total92453977
TQS in the emergency departmentb
    Positive644136.62 (5.25-255.3)
    Inconclusive9331.76 (0.58-5.38)
    Negative195490.22 (0.20-0.26)
    Total93253984
Total blood/lab-TQS at laboratoryb
    Positive7790c89.08 (5.64-1405)
    Inconclusive360c4.12 (0.26-67.0)
    Negative112520.12 (0.10-0.15)
    Total92752979
Serum/lab-TQS at laboratoryb
    Positive8000c92.70 (5.87-1462)
    Inconclusive300c3.48 (0.219-57.0)
    Negative102530.11 (0.09-0.13)
    Total93253985
  • a Protected is defined as >0.1 IU/ml in ELISA; not protected is defined as ≤0.1 IU/ml in ELISA.

  • b Serum/lab-TQS at laboratory is considered positive beyond a threshold of 0.1 IU/ml; total blood/lab-TQS in the laboratory and in emergency department are considered positive beyond a threshold of 0.2 IU/ml.

  • c Likelihood ratios were calculated by taking the 0 value as 0.5.