TABLE 1.

Sensitivity of the C6 test and the standard Lyme ELISA (historically tested) in culture-confirmed single- and multiple-EM patients

Time pointNo. (%) of patients diagnosed positive by indicated test
Patients with single EM (n = 93)Patients with multiple EM (n = 27)Total patients (n = 120)
C6 test (n = 93)Standard ELISAa (n = 91)C6 test (n = 27)Standard ELISA (n = 26)C6 test (n = 120)Standard ELISA (n = 117)
Baseline38 (41)24 (26)23 (85)21 (81)61 (51)45 (38)
Convalescence41 (44)25 (27)3 (11)3 (11)44 (37)28 (24)
Total79 (85)49 (54)26 (96)24 (92)105 (88)73 (62)
  • a The standard ELISA is the commonly used diagnostic ELISA for Lyme disease that makes use of whole-cell extract as antigen.