TABLE 1.

Mapping of epitopes on the N protein of PPRV Nig75/1 straina

Competing MAb (isotype)DomainLabeled MAb
33-4P-3H12P-13A938-4P-14C6P-9H10P-11A6
33-4 (IgG1)A-I++
P-3H12 (IgG2a)A-II+++++
P-13A9 (IgG2b)A-II+++++++
38-4 (IgG1)A-II+++++++++
P-14C6 (IgM)C-I++++++
P-9H10 (IgG1)C-II+++++
P-11A6 (IgG2b)C-II++++++++++++
  • a −, <50% competition by unlabeled MAb at 1:100; +, >50% competition by unlabeled MAb at 1:100; ++, >50% competition by unlabeled MAb at 1:1,000; +++, >50% competition by unlabeled MAb at 1:10,000.