TABLE 3.

Comparison of NO responses by PBMC from M. bovis-infected cattle to responses by cattle naturally sensitized to M. avium

GroupNO responsea to recall antigen:
PPDaPPDbrESAT-6:CFP-10
M. bovis-infected (6 mo postinfection)196.1b (46.1)403.3b (86.4)415.7b (98.4)
M. avium-exposed (natural exposure)49.1 (9.1)−4.5 (9.9)−19.0 (10.1)
  • a Values are the mean NO responses (in nanograms per milliliter) (n = 8) of PBMC to antigen stimulation minus their response to medium alone after 72 h. Values in parentheses are the standard errors of the means.

  • b Significantly different from the response by M. avium-exposed cattle (P < 0.01).