TABLE 5.

Presence of specific IgM and IgG antibodies in patients with acute and persistent brucellosis

Stage of illnessaNo. of patients with positive result (% positive, 95% CI) in the indicated assay
SAT, ≥1:320SAT, ≥1:160SAT-DTT, ≥1:160SAT-DTT, ≥1:80SAT-DTT, ≥4-fold titer reductionCoombs, ≥1:320IgM flow, ≥1+IgG flow, ≥1+IgM + IgG flow, ≥1+b
Acute (n = 23)16 (70, 47-86)20 (87, 65-97)11 (48, 27-69)13 (57, 35-76)15 (65, 43-83)23 (100, 82-100)14 (61, 39-80)17 (74, 51-89)21 (91, 71-99)
Persistent (n = 13)7 (54, 26-80)9 (69, 39-90)3 (23, 6-54)5 (39, 15-68)5 (39, 15-68)13 (100, 72-100)4 (31, 10-61)10 (77, 46-94)12 (92, 62-100)
  • a Acute, <3 months of illness at diagnosis; persistent, >3 months of illness at diagnosis.

  • b Positive (≥1+) test result in at least one of the two flow assays.