TABLE 5.

Effect of urine concentration by ultrafiltration on inhibition ELISA results with urine from colonized or intravenously infected rabbitsa

Organism% Inhibition ± SE (n)Pb
1× urine10× urine
C. albicans
    Lccocq62.4 ± 3.4 (3)91.5 ± 0.8 (3)<0.001
    36B43.8 ± 2.3 (3)71.2 ± 1.0 (3)<0.001
    3181A46.4 ± 3.6 (3)65.5 ± 0.7 (3)<0.01
    Q1638.2 ± 3.6 (3)40.1 ± 1.6 (3)NSc
    B31126.0 ± 2.5 (3)30.9 ± 0.9 (3)NS
    Colonizedd0.6 ± 0.6 (6)0 ± 0 (6)0e
C. tropicalis6.2 ± 2.9 (6)0 ± 0 (3)0
C. neoformans6.8 ± 3.3 (6)10.9 ± 0.8 (3)NS
A. fumigatus8.8 ± 1.9 (6)4.5 ± 2.3 (6)0
  • a Urine was collected from rabbits on the day of necropsy (day 4 or 5).

  • b P value for a significant increase in ELISA inhibition results by 10× concentration of urine. Mean percent ELISA inhibition ± SE by column effluents, 3.2 ± 0.9 (n = 21).

  • c NS, no significant increase in ELISA inhibition by 10× concentration of urine.

  • d Rabbits were colonized by intraurethral installation of C. albicans strain 36B.

  • e No increase in ELISA inhibition by 10× concentration of urine.