TABLE 3.

Predicted vaccine efficacy and 95% CIs estimated for unvaccinated and vaccinated children with titers below the different SBA cutoffs 1 month after vaccination with the MCC vaccine measured by SBA

Group and cutoff% Individuals with titers below cutoffPredicted % vaccine efficacy (95% CI)
VaccinatedUnvaccinated
Infants
    1:40.084.0100 (86-100)
    1:81.987.698 (85-100)
    1:161.990.598 (86-100)
    1:321.993.598 (84-100)
    1:641.994.798 (86-100)
    1:1283.896.496 (85-99)
Toddlers
    1:44.384.395 (85-98)
    1:88.687.390 (79-95)
    1:1612.991.486 (74-92)
    1:3217.192.982 (69-89)
    1:6427.195.171 (58-81)
    1:12832.996.666 (52-76)
Preschool children
    1:40.090.4100 (95-100)
    1:80.093.3100 (95-100)
    1:162.594.397 (92-99)
    1:324.195.296 (90-98)
    1:644.997.195 (89-98)
    1:1289.897.690 (83-94)