TABLE 1.

Characteristics of affinity chromatography-purified antibodies to modified LDL

Antibody (n)Immunoglobulin concn (mg/liter)Kd (mol/liter)
IgGIgMIgAIgG1IgG2IgG3IgG4
Human oxLDL antibody (30)88 ± 3020 ± 112.4 ± 1.362 ± 236.2 ± 2.518 ± 110.4 ± 0.2(1.02 ± 1.1) × 10−8
Human AGE-LDL antibody (7)44 ± 2514 ± 72.6 ± 1.826 ± 153.1 ± 4.214.5 ± 9.6NDa(0.48 ± 0.25) × 10−8
IgG from rabbit and human ApoB antibody (3)(9.34) × 10−11
  • a ND, not detected.