TABLE 2.

BT of the intestinal microbiota in healthy mice and in mice with TNBS-induced colitis

Pretreatment (oral)Treatment (i.r.a)nbColitisMLNcSpleenc
NaHCO3None5No2550
NCIMB8826 (in NaHCO3)None9No2033
MG1363 (in NaHCO3)None8No037
NoneTNBS-ethanol5Yes8080
NoneEthanol5No025
NCIMB8826 (in NaHCO3)TNBS-ethanol8Yes7562
MG1363 (in NaHCO3)TNBS-ethanol8Yes8643
  • a i.r., intrarectal administration.

  • b n, number of animals per group.

  • c Data are the percentages of organs positive for bacterial cultures (detection limit, ≥100 CFU/organ).