TABLE 2.

TCR Vβ family analysis in CD4 T cells in HIV-infected children by CDR3 length and FC analysis

Patient no.aPCRbFC
SkewingClonal dominanceExpansionDepletion
1NoneNoneNone12
223, 24None3, 5.1, 14, 16, 179, 11, 12
3NDNDNone5.2, 12, 13.1
411, 21, 23, 24None8, 11, 207
523None811, 12
64, 21, 23None1412
7NDND3, 9, 14, 1812
823None9, 16, 1812
923None35.1, 12
101, 4, 16, 18, 23None9, 11, 14, 177, 12
114, 5.1, 8, 20, 23, 24None8, 11, 16, 1712
124, 23None5.1, 8, 9, 16, 22None
1323None11None
14NDND3, 7, 169, 11, 12
1523None149, 12, 13.1
164, 21, 23, 24None165.1, 9, 12, 18
175.2, 9, 11None5.2, 9, 11, 13.1, 14, 17, 188, 12
1821, 23, 24None3, 5.2, 11, 13.1, 147, 12
19NoneNone3, 14, 1712, 20
214, 23, 24None8, 13.1, 14, 167, 9, 12
2223, 24None8, 14, 16, 187, 12
Total no. of TCR Vβ families altered (no. of patients)42 (18)0 (18)60 (21)40 (21)
  • a ND, not done.

  • b Analysis not done for patient 20.