TABLE 4.

Prevalence of C. pneumoniae in monosymptomatic MS patients

PatientAge (yr)GenderCSF characteristicsInitial eventaIgG indexbOCc bandsBrain MRI resultsdCervical cord MRI resultsPCR assay results
VUMCeUSF with MOMP primerf
Cell count (no. of cells/μl)Protein concn (mg/dl)Glucose concn (mg/dl)VU-MOMPTong and Sillis
127M215953SC0.55NormalSingle T2 lesion+
232M103858SC1.23NormalTwo T2 lesions+++
342M38670SC0.51NormalEnhancing Lesion
427F01351ON0.46NormalNormal++
538F12464BS0.5Two T2 PV lesionsNormal
645F02350SC0.99+NormalEnhancing Lesion+++
752M7Unknown71ON0.61Three PV lesionsNDg
834F15055ON0.6Multiple PV lesionsND+
939F14360BS0.39Multiple PV lesionsND+ND
1033F15657BS0.45+Multiple PV lesionsNormal
1131F94962ON1.41+Single enhancing lesionsSingle T2 lesion+++
1228F23254ON0.74+NormalSingle T2 lesion+
1357F11553SCND+Brian NormalNDNDND
1447F25252BSND+Single T2 lesion PonsNDNDND
1542F212665SCNDNSWM abnormalNDNDND
1641F12165BSND+3 NSWM lesionsND+NDND
1725F02759BSND+4 NSWM lesionsND+NDND
  • a Abbreviation for locations of initial events: SC, spinal cord; ON, optic nerve; BS, brain stem.

  • b IgG, immunoglobulin G.

  • c OC, oligoclonal.

  • d PV, periventricular; NSWM, nonspecific white matter.

  • e The total numbers of samples positive were 7 and 4 with the VU-MOMP and Tong and Sillis primers, respectively.

  • f The total number of samples positive was 2.

  • g ND, not done.