TABLE 3.

Significant associations between demographic characteristics and lymphocyte subsets, calculated by multivariate linear regression

Lymphocyte subsetCovariateRegression coefficientaP value
Total CD4+Female0.07340.0004
CD4+ naïveNone
CD4+ memoryFemale0.1296<0.0001
Age0.01390.0097
Total CD8+Female−0.12710.032
Gender × raceb0.19010.011
CD8+ naïveNone
CD8+ memoryAge0.02280.018
African-American−0.32930.0002
Gender × racec0.33110.0016
CD16+Female−0.09050.038
CD19+Age−0.03410.0001
Age × genderd0.02540.0329
  • a Value obtained by taking the log10 of cell counts.

  • b African-American females have higher total CD8+ cell counts. No race effect was observed for males.

  • c African-American males have lower CD8+ memory cell counts. No race effect was observed for females.

  • d Males have lower CD19+ cell counts with increasing age. No age effect was observed for females.