TABLE 3.

Comparison of the degrees of lymphocyte depletion of different lymphoid tissues with respect to the apparent amount of PCV2 DNA genome observed after ISH

Level of PCV2 DNA (no. of pigsb)No. of PCV2-positive pigs showing indicated degree of lymphocyte depletion in indicated tissuea
Superficial inguinal LNcMesenteric LNPeyer's patchesTonsilSpleen (PALSd)
B zoneeT zonefB zoneT zoneB zoneT zoneB zonegT zoneh
12 or 312 or 312 or 312 or 312 or 312 or 312 or 312 or 312 or 3
Low (7)400030101111301010
High (17)015890171160161161134957
  • a Score of lymphocyte depletion degree: 1, slight; 2, moderate; 3, severe.

  • b Total number of pigs, including those not showing lymphocyte depletion.

  • c LN, lymph node.

  • d PALS, periarteriolar lymphoid sheaths; P = 0.07.

  • e B zone, B-cell-dependent area.

  • f T zone, T-cell-dependent area.

  • g P < 0.01; for other groups, P < 0.001, except as indicated.

  • h P < 0.05.