TABLE 4.

Mean levels of soluble CAM in serum as measured by ELISA

Group no.Subject groupNo. of subjectsMean level (ng/ml)a in serum ± SE
sVCAMsICAM
1PD CVD26896.5 ± 130.0289.1 ± 24.8
2PD+ CVD20953.0 ± 188.9315.9 ± 36.0
3PD CVD+181,538.1 ± 152.5333.3 ± 29.1
4PD+ CVD+161,334.9 ± 166.3293.0 ± 31.7
  • a Overall P values were as follows: sVCAM, 0.0054 (P < 0.05); and sICAM, 0.6495. For post hoc comparisons for sVCAM, P = 0.0015 (groups 1 and 3), 0.0399 (groups 1 and 4), and 0.0257 (groups 2 and 3). A summary table of sCAM levels was determined by ELISA analysis. The data were analyzed by using ANCOVA and reported as the group mean ± SE, with an adjustment for smoking. Normal levels as reported by the kit manufacturers were as follows: sVCAM range, 395 to 714 ng/ml (mean, 553 ng/ml); and sICAM range, 114.7 to 306.4 ng/ml (mean, 210.6 ng/ml).