TABLE 1.

IHC detection of PrPSc-positive cells in DRLN cells from four scrapie-infected sheep mixed with 3 × 106 PBLs from a normal sheep

No. of DRLN cells added to 3 × 106 PBLsResult fora:
Sheep 927Sheep 1243Sheep 1437Sheep 1443
3 × 104NDb+ND+
3 × 103++++
3 × 102+
  • a +, presence of PrPSc-positive cells in a given number of DRLN cells mixed with 3 × 106 PBLs.

  • b ND, not determined.