TABLE 1.

Clinical features at the acute phase in patients infected with V. cholerae O1 and O139

ParameterAdultsChildren
O1 infectedO139 infectedHealthy controlsO1 infectedO139 infectedHealthy controls
Median age in yr (range)25 (18-44)d29 (19-40)27 (22-40)5 (2-8)6 (2-9)4 (3-7)
Median duration of illnessa in h (range)8 (5-14)8 (6-17)NAe12 (5-14)11 (3-13)NA
No. (%) with dehydrationb12 (100)13 (100)NA9 (90)9 (100)NA
No. (%) with temp of >37.8°C00NA00NA
Blood leukocyte count (102/mm3)c107 (103-112)*121 (113-129)*92 (90-94)111 (106-117)*109 (101-118)*94 (91-100)
Blood lymphocyte count (%)32 (30-34)31 (29-34)36 (34-38)39.4 (37-42)32 (29-35)44 (41-48)
Blood PMN count (%)c64 (62-66)*63 (60-67)*56 (54-58)53 (49.6-56.5)58 (53-63)45.2 (43-50)
No. (%) with >50 leukocytes/high-powered fieldf1 (7.6)1 (8)0000
Creatinine concn in serum in μmol/liter (range)c95.7 (87-105)*110 (89-136)*70 (67-72)67 (63.5-71)*82 (71-95)*49 (47-51)
Creatinine concn in urine in μmol/liter (range)c3,617 (2,092-11,003)*3,410 (2,633-5,897)*1,918 (1,407-2,298)2,989 (1,742-3,984)*2,900 (1,851-3,845)*865 (510-1,451)
  • a That is, duration of illness before hospitalization.

  • b The numbers and percentages of patients with severe dehydration are shown.

  • c Statistical significance (P ≤ 0.05) between the acute stage in O1 and O139 patients and healthy controls is indicated by an asterisk.

  • d Results are expressed as medians with ranges (25th to 75th percentiles) in parentheses.

  • e NA, not applicable in the case of healthy controls.

  • f As determined by microscopic examination of stool samples.