Table 1.

Therapeutic and immunological characteristics of relevant clinical trials including IL-2 for the treatment of HIV-positive patients

Investigators (reference)Baseline CD4 count (no. of cells/mm3)TreatmentCD4 increase [no. of cells/mm3 (%)] after:
ARTaIL-2 treatment
Simonelli et al. (58)200–500RTIs+60+256
Davey et al. (13)>200RTIsND>200 (44), 0–200 (33)
Emery et al. (19)100–500RTIs+153+368
Levy et al. (36)250–550RTIs+55+564
Davey et al. (14)200–500HAART+64+384
Ruxrungtham et al. (55)≥350HAART+42+252
Abrams et al.c ≥300HAART+22+276
  • a ART, antiretroviral therapy.

  • b ND, not determined.

  • c Addendum Abstr. 40th Intersci. Conf. Antimicrob. Agents Chemother., abstr. L11, p. 24, 2000.