Table 2.

Comparison of IFN-γ release in four patients with minimal TB and four infected cattle in response to the combination of ESAT-6 and CFP10 or the single components

GroupSubjectIFN-γ releasea in response to:
PPD or PPDBESAT-6CFP10ESAT-6/CFP10
PatientsA20,9272,1692252,910
B17,1646,3632,6429,173
C3,004503,2574,181
D21,0326,8706,15013,620
CattleA31.45.91.86.4
B23.96.29.68.7
C55.512.022.119.8
D19.12.110.87.2
  • a IFN-γ was measured by ELISA. Results for humans are expressed as mean picograms per milliliter from triplicate wells and are shown as delta values (see Materials and Methods). Results for cattle are expressed as mean ODI values (OD of antigen-stimulated well/OD of control well) from duplicate cultures.