Table 1.

Specificities and sensitivities of various individual proteins and combinations of homolous proteins in IgG WB

CategoryaAntigenStrainSpecificity (%)bSensitivity (%)c
Ip83/100PKa2100.028.0
p83/100PKo100.027.5
p83/100PBi99.332.8
p83/100All 3 strainsd99.334.4
p58PKa299.337.0
p58PKo97.246.6
p58PBi99.334.4
p58All 3 strainsd97.250.3
p39PKa297.916.9
p39PKo98.637.6
p39PBi100.035.4
p39All 3 strainsd96.540.7
p30PKa296.527.5
p30PKo99.324.9
p30PBi97.928.6
p30All 3 strainsd95.733.3
OspCPKa297.214.3
OspCPKo99.314.3
OspCPBi97.920.6
OspCAll 3 strainsd94.330.7
p21PKa2100.025.4
p21PKo100.023.3
p21PBi100.028.6
p21All 3 strainsd100.030.7
IIp75PKa290.124.9
p75PKo92.219.0
p75PBi88.727.0
p66PKa2100.011.1
p66PKo95.77.4
p66PBi97.98.5
p60PKa292.221.2
p60PKo95.75.8
p60PBi90.823.3
p41PKa264.553.4
p41PKo78.745.5
p41PBi65.256.6
OspAPKa299.30.5
OspAPKo97.92.1
OspAPBi95.74.8
IIIp56PKa2100.029.6
p43PKo93.638.6
p35PKo97.212.7
p17aPKa2100.013.2
p17PKo96.540.7
p17bPBi99.315.9
p14PKo99.329.6
  • a Category I, highly specific antigens with sensitivities of >14%; homologs of all three strains known. II, well-known antigens with low specificity and/or low sensitivity; homologs of all three strains known. III, antigens identified in only one strain; interesting as additional diagnostic antigens.

  • b Specificities were determined with the data of 141 sera of the control group.

  • c Sensitivities were determined with the data of 189 sera from patients at different stages of LB.

  • d A positive result in the combination means that at least one of the antigens was reactive.