TABLE 2.

Cross-HI test with antiserum obtained by DNA vaccination

AntigenaAntiserum titerb
H1H2H3H4H5NAH5EAH6H7NAH7EAH8H9H10H11H12H13H14H15
H1N1128c
H2N812844
H3N8128
H4N6128
H5N9-NA12832
H5N1-EA64128
H6N844128
H7N2-NA12832
H7N1-EA128128
H8N4128
H9N24128
H10N7128
H11N14128
H12N58128
H13N64128
H14N5816
H15N916128
  • a The same viruses used for DNA vaccine construction were used as the antigen, except for the H4 antigen, where A/duck/NJ/5406-27/94 was used. NA, North American lineage virus; EA, Eurasian lineage virus.

  • b The HI titers of the sera, except H14 serum, were adjusted to 1:128 with the homologous antigen.

  • c − indicates an HI titer less than 4.