TABLE 1.

Volumes and total immunoglobulin concentrations in undiluted genital secretions collected from women using different types of contraceptive methods

Genital specimen and parameterImmunization group
IUD (n = 9)OCP (n = 8)NPC (n = 9)
Cervical secretion
    Vol (μl)a152 (113-205)39 (30-52)196 (154-249)
    IgA concn (μg ml−1)b225 (150-338)149 (78-284)144 (85-243)
    IgG concn (μg ml−1)b540 (366-796)508 (243-1,062)288 (137-607)
Vaginal fluid
    Vol (μl)c204 (171-244)140 (119-175)133 (98-179)
    IgA concn (μg ml−1)292 (218-393)76 (41-142)116 (65-207)
    IgG concn (μg ml−1)1,187 (800-1,762)506 (245-1,040)502 (282-891)
  • a Cervical secretions were collected with a syringe. Volumes are expressed as geometric means (95% confidence intervals) of pre- and postvaccination specimens for the whole group.

  • b Geometric means (95% confidence intervals) of total immunoglobulin concentrations in specimens collected before and after two vaginal vaccinations for the whole group.

  • c Vaginal fluids eluted from two ophthalmic sponges were pooled. Volumes are expressed as geometric means (95% confidence intervals) of pre- and postvaccination specimens for the whole group.