RT Journal Article
SR Electronic
T1 Clinical Evaluation of a (1,3)-β-<span class="sc">d</span>-Glucan Assay for Presumptive Diagnosis of <em>Pneumocystis jiroveci</em> Pneumonia in Immunocompromised Patients
JF Clinical and Vaccine Immunology
JO Clin Vaccine Immunol
FD American Society for Microbiology
SP 1524
OP 1526
DO 10.1128/CVI.00276-09
VO 16
IS 10
A1 Del Bono, Valerio
A1 Mularoni, Alessandra
A1 Furfaro, Elisa
A1 Delfino, Emanuele
A1 Rosasco, Lorenzo
A1 Miletich, Franca
A1 Viscoli, Claudio
YR 2009
UL http://cvi.asm.org/content/16/10/1524.abstract
AB (1,3)-β-d-Glucan (BG) is a component of the Pneumocystis jiroveci cell wall. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels. Serum from all 16 presumptive PCP patients and from 2/15 patients with non-PCP was positive for BG. Results indicate that BG is a reliable marker for diagnosing PCP.