DOI: 10.1128/CDLI.5.3.415-417.1998
ABSTRACT
We wished to determine the prevalence of immunoglobulin A (IgA) deficiency in patients with the chromosome 22q11.2 deletion syndrome. A total of 32 patients with the chromosome 22q11.2 deletion were examined for IgA deficiency. We report a 13% (n = 4) prevalence of IgA deficiency in patients with this syndrome. The odds ratio of IgA deficiency in this population is 14.20 (P< 0.0001). This confirms the occurrence of significant humoral deficits in this predominantly cellular immunodeficiency.
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