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Clinical and Vaccine Immunology
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Vaccines

Impaired Antigen-Specific Immune Response to Vaccines in Children with Antibody Production Defects

Aleksandra Szczawinska-Poplonyk, Anna Breborowicz, Husam Samara, Lidia Ossowska, Grzegorz Dworacki
S. A. Plotkin, Editor
Aleksandra Szczawinska-Poplonyk
aDepartment of Pediatric Pneumonology, Allergology and Clinical Immunology, III Chair of Pediatrics, Poznan University of Medical Science, Poznan, Poland
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Anna Breborowicz
aDepartment of Pediatric Pneumonology, Allergology and Clinical Immunology, III Chair of Pediatrics, Poznan University of Medical Science, Poznan, Poland
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Husam Samara
bDepartment of Immunology, Chair of Clinical Immunology, Poznan University of Medical Sciences, Poznan, Poland
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Lidia Ossowska
aDepartment of Pediatric Pneumonology, Allergology and Clinical Immunology, III Chair of Pediatrics, Poznan University of Medical Science, Poznan, Poland
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Grzegorz Dworacki
bDepartment of Immunology, Chair of Clinical Immunology, Poznan University of Medical Sciences, Poznan, Poland
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S. A. Plotkin
Roles: Editor
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DOI: 10.1128/CVI.00148-15
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    FIG 1

    Subgroups of patients studied regarding the deficiency of major classes of immunoglobulins.

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    FIG 2

    Individual serum immunoglobulin G (a), A (b), and M (c) levels in children studied. Min, minimum; max, maximum.

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    FIG 3

    Levels of antigen-specific postvaccination antibodies: anti-HBs (a), anti-tetanus toxoid (b), anti-diphtheria toxoid (c), and anti-PRP Hib (d).

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    FIG 4

    Relative values (a) and absolute counts (b) of transitional B lymphocytes in children with hypogammaglobulinemia.

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    FIG 5

    Relative values (a) and absolute counts (b) of plasmablasts in children with hypogammaglobulinemia.

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Impaired Antigen-Specific Immune Response to Vaccines in Children with Antibody Production Defects
Aleksandra Szczawinska-Poplonyk, Anna Breborowicz, Husam Samara, Lidia Ossowska, Grzegorz Dworacki
Clinical and Vaccine Immunology Jul 2015, 22 (8) 875-882; DOI: 10.1128/CVI.00148-15

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Impaired Antigen-Specific Immune Response to Vaccines in Children with Antibody Production Defects
Aleksandra Szczawinska-Poplonyk, Anna Breborowicz, Husam Samara, Lidia Ossowska, Grzegorz Dworacki
Clinical and Vaccine Immunology Jul 2015, 22 (8) 875-882; DOI: 10.1128/CVI.00148-15
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