Serodiagnosis as Adjunct Assay for Pertussis Infection in São Paulo, Brazil

DOI: 10.1128/CVI.00760-13

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FIG 1
Proportion of positive pertussis cases diagnosed by culture and/or RT-PCR, PT ELISA, and combined assays, stratified by age. m, months; y, years.
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FIG 2
Proportion of positive cases diagnosed by culture and/or RT-PCR and PT ELISA stratified by time since cough onset in weeks (w). The total number of subjects per time point was used as the denominator. (A) Analysis based on time of symptoms for all reported cases; (B) cases separated by age groups: group 1 (<1 year), group 2 (1 to 6 years), and group 3 (≥7 years).

TABLE 1

Characteristics of the studied population according to age and positivity to pertussis laboratory analysis

TABLE 2

Frequencies of positive pertussis cases in different age groups by culture and/or RT-PCR and serology (PT-ELISA)

Characteristic	Group 1 (<1 yr)	Group 2 (1–6 yr)	Group 3 (≥7 yr)
No. of pertussis-positive cases/total no. of cases	101/260	31/81	94/162
No. (%) of positive cases by culture and/or RT-PCR	61 (60.4)^{^a}	2 (6.4)	3 (3.2)
No. (%) of positive cases by PT-ELISA	18 (17.8)	25 (80.6)	81 (86.2)
No. (%) of positive cases by combined assays^{^b}	22 (21.8)	4 (13)	10 (10.6)
No. of seronegative cases	150	47	62
P^{^c}	<0.0001	<0.0001	<0.0001