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Diagnostic Laboratory Immunology

A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection

Luca Formichella, Laura Romberg, Christian Bolz, Michael Vieth, Michael Geppert, Gereon Göttner, Christina Nölting, Dirk Walter, Wolfgang Schepp, Arne Schneider, Kurt Ulm, Petra Wolf, Dirk H. Busch, Erwin Soutschek, Markus Gerhard
Luca Formichella
aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
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Laura Romberg
aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
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Christian Bolz
aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
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Michael Vieth
cDepartment of Pathology, Klinikum Bayreuth, Bayreuth, Germany
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Michael Geppert
bDoctor's Practice for Gastroenterology, Bayreuth, Germany
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Gereon Göttner
dMikrogen GmbH, Neuried, Germany
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Christina Nölting
dMikrogen GmbH, Neuried, Germany
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Dirk Walter
aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
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Wolfgang Schepp
eDepartment of Gastroenterology, Hepatology and Gastrointestinal Oncology, Bogenhausen Academic Teaching Hospital, Munich, Germany
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Arne Schneider
eDepartment of Gastroenterology, Hepatology and Gastrointestinal Oncology, Bogenhausen Academic Teaching Hospital, Munich, Germany
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Kurt Ulm
fInstitute for Medical Statistics and Epidemiology, Technische Universität München, Munich, Germany
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Petra Wolf
fInstitute for Medical Statistics and Epidemiology, Technische Universität München, Munich, Germany
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Dirk H. Busch
aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
gDZIF German Centre for Infection Research, Munich, Germany
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Erwin Soutschek
dMikrogen GmbH, Neuried, Germany
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Markus Gerhard
aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
gDZIF German Centre for Infection Research, Munich, Germany
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DOI: 10.1128/CVI.00433-13
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Article Information

DOI 
https://doi.org/10.1128/CVI.00433-13
PubMed 
24006137

Published By 
American Society for Microbiology Journals
History 
  • Received July 11, 2013
  • Returned for modification August 9, 2013
  • Accepted August 27, 2013
  • Published online October 25, 2013.

Copyright & Usage 
Copyright © 2013, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (September 04, 2013).
  • You are viewing the most recent version of this article.

Author Information

  1. Luca Formichellaa,
  2. Laura Romberga,
  3. Christian Bolza,
  4. Michael Viethc,
  5. Michael Geppertb,
  6. Gereon Göttnerd,
  7. Christina Nöltingd,
  8. Dirk Waltera,
  9. Wolfgang Scheppe,
  10. Arne Schneidere,
  11. Kurt Ulmf,
  12. Petra Wolff,
  13. Dirk H. Buscha,g,
  14. Erwin Soutschekd and
  15. Markus Gerharda,g
  1. aInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany
  2. bDoctor's Practice for Gastroenterology, Bayreuth, Germany
  3. cDepartment of Pathology, Klinikum Bayreuth, Bayreuth, Germany
  4. dMikrogen GmbH, Neuried, Germany
  5. eDepartment of Gastroenterology, Hepatology and Gastrointestinal Oncology, Bogenhausen Academic Teaching Hospital, Munich, Germany
  6. fInstitute for Medical Statistics and Epidemiology, Technische Universität München, Munich, Germany
  7. gDZIF German Centre for Infection Research, Munich, Germany
  • Address correspondence to Markus Gerhard, markus.gerhard{at}mikrobio.med.tum.de.
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A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection
Luca Formichella, Laura Romberg, Christian Bolz, Michael Vieth, Michael Geppert, Gereon Göttner, Christina Nölting, Dirk Walter, Wolfgang Schepp, Arne Schneider, Kurt Ulm, Petra Wolf, Dirk H. Busch, Erwin Soutschek, Markus Gerhard
Clinical and Vaccine Immunology Oct 2013, 20 (11) 1703-1710; DOI: 10.1128/CVI.00433-13

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A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection
Luca Formichella, Laura Romberg, Christian Bolz, Michael Vieth, Michael Geppert, Gereon Göttner, Christina Nölting, Dirk Walter, Wolfgang Schepp, Arne Schneider, Kurt Ulm, Petra Wolf, Dirk H. Busch, Erwin Soutschek, Markus Gerhard
Clinical and Vaccine Immunology Oct 2013, 20 (11) 1703-1710; DOI: 10.1128/CVI.00433-13
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