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Clinical Immunology

Antigen-Specific Memory T Cell Responses after Vaccination with an Oral Killed Cholera Vaccine in Bangladeshi Children and Comparison to Responses in Patients with Naturally Acquired Cholera

Mohammad Arifuzzaman, Rasheduzzaman Rashu, Daniel T. Leung, M. Ismail Hosen, Taufiqur Rahman Bhuiyan, M. Saruar Bhuiyan, Mohammad Arif Rahman, Farhana Khanam, Amit Saha, Richelle C. Charles, Regina C. LaRocque, Ana A. Weil, John D. Clements, Randall K. Holmes, Stephen B. Calderwood, Jason B. Harris, Edward T. Ryan, Firdausi Qadri
Mohammad Arifuzzaman
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
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Rasheduzzaman Rashu
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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Daniel T. Leung
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA
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M. Ismail Hosen
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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Taufiqur Rahman Bhuiyan
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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M. Saruar Bhuiyan
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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Mohammad Arif Rahman
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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Farhana Khanam
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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Amit Saha
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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Richelle C. Charles
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA
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Regina C. LaRocque
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA
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Ana A. Weil
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
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John D. Clements
dDepartment of Microbiology and Immunology, Tulane University Medical Center, New Orleans, Louisiana, USA
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Randall K. Holmes
eDepartment of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
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Stephen B. Calderwood
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA
fDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA
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Jason B. Harris
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
gDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
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Edward T. Ryan
bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA
hDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA
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Firdausi Qadri
aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
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DOI: 10.1128/CVI.00196-12
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Article Information

DOI 
https://doi.org/10.1128/CVI.00196-12
PubMed 
22739692

Published By 
American Society for Microbiology Journals
History 
  • Received April 4, 2012
  • Returned for modification April 25, 2012
  • Accepted June 19, 2012
  • Published online July 31, 2012.

Copyright & Usage 
Copyright © 2012, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (June 27, 2012).
  • You are viewing the most recent version of this article.

Author Information

  1. Mohammad Arifuzzamana,b*,
  2. Rasheduzzaman Rashua,
  3. Daniel T. Leunga,b,c,
  4. M. Ismail Hosena,
  5. Taufiqur Rahman Bhuiyana,
  6. M. Saruar Bhuiyana,
  7. Mohammad Arif Rahmana,
  8. Farhana Khanama,
  9. Amit Sahaa,
  10. Richelle C. Charlesb,c,
  11. Regina C. LaRocqueb,c,
  12. Ana A. Weilb,
  13. John D. Clementsd,
  14. Randall K. Holmese,
  15. Stephen B. Calderwoodb,c,f,
  16. Jason B. Harrisb,g,
  17. Edward T. Ryanb,c,h and
  18. Firdausi Qadria
  1. aCentre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
  2. bDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA
  3. cDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA
  4. dDepartment of Microbiology and Immunology, Tulane University Medical Center, New Orleans, Louisiana, USA
  5. eDepartment of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
  6. fDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA
  7. gDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
  8. hDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA
  • Address correspondence to Firdausi Qadri, fqadri{at}icddrb.org.
  • ↵* Present address: Mohammad Arifuzzaman, Cell and Molecular Biology Program, Duke University Medical Center, Durham, North Carolina, USA.

  • E.T.R. and F.Q. are co-senior authors.

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Antigen-Specific Memory T Cell Responses after Vaccination with an Oral Killed Cholera Vaccine in Bangladeshi Children and Comparison to Responses in Patients with Naturally Acquired Cholera
Mohammad Arifuzzaman, Rasheduzzaman Rashu, Daniel T. Leung, M. Ismail Hosen, Taufiqur Rahman Bhuiyan, M. Saruar Bhuiyan, Mohammad Arif Rahman, Farhana Khanam, Amit Saha, Richelle C. Charles, Regina C. LaRocque, Ana A. Weil, John D. Clements, Randall K. Holmes, Stephen B. Calderwood, Jason B. Harris, Edward T. Ryan, Firdausi Qadri
Clinical and Vaccine Immunology Jul 2012, 19 (8) 1304-1311; DOI: 10.1128/CVI.00196-12

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Antigen-Specific Memory T Cell Responses after Vaccination with an Oral Killed Cholera Vaccine in Bangladeshi Children and Comparison to Responses in Patients with Naturally Acquired Cholera
Mohammad Arifuzzaman, Rasheduzzaman Rashu, Daniel T. Leung, M. Ismail Hosen, Taufiqur Rahman Bhuiyan, M. Saruar Bhuiyan, Mohammad Arif Rahman, Farhana Khanam, Amit Saha, Richelle C. Charles, Regina C. LaRocque, Ana A. Weil, John D. Clements, Randall K. Holmes, Stephen B. Calderwood, Jason B. Harris, Edward T. Ryan, Firdausi Qadri
Clinical and Vaccine Immunology Jul 2012, 19 (8) 1304-1311; DOI: 10.1128/CVI.00196-12
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    • ABSTRACT
    • INTRODUCTION
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    • RESULTS
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