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Vaccines

The Oral, Live Attenuated Enterotoxigenic Escherichia coli Vaccine ACE527 Reduces the Incidence and Severity of Diarrhea in a Human Challenge Model of Diarrheal Disease

Michael J. Darsley, Subhra Chakraborty, Barbara DeNearing, David A. Sack, Andrea Feller, Charlotte Buchwaldt, A. Louis Bourgeois, Richard Walker, Clayton D. Harro
Michael J. Darsley
aTD Vaccines A/S, Skorping, Denmark
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Subhra Chakraborty
bJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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Barbara DeNearing
bJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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David A. Sack
bJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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Andrea Feller
bJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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Charlotte Buchwaldt
aTD Vaccines A/S, Skorping, Denmark
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A. Louis Bourgeois
cPATH, Washington, DC, USA
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Richard Walker
cPATH, Washington, DC, USA
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Clayton D. Harro
bJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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DOI: 10.1128/CVI.00364-12
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Article Information

DOI 
https://doi.org/10.1128/CVI.00364-12
PubMed 
23035175

Published By 
American Society for Microbiology Journals
History 
  • Received June 15, 2012
  • Returned for modification July 25, 2012
  • Accepted September 24, 2012
  • Published online November 27, 2012.

Copyright & Usage 
Copyright © 2012, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (October 03, 2012).
  • You are viewing the most recent version of this article.

Author Information

  1. Michael J. Darsleya*,
  2. Subhra Chakrabortyb,
  3. Barbara DeNearingb,
  4. David A. Sackb,
  5. Andrea Fellerb,
  6. Charlotte Buchwaldta,
  7. A. Louis Bourgeoisc,
  8. Richard Walkerc and
  9. Clayton D. Harrob
  1. aTD Vaccines A/S, Skorping, Denmark
  2. bJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
  3. cPATH, Washington, DC, USA
  • Address correspondence to Michael J. Darsley, mjd{at}mdbiologic.co.uk.
  • ↵* Present address: MD Biologic, Babraham, Cambridge, United Kingdom.

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The Oral, Live Attenuated Enterotoxigenic Escherichia coli Vaccine ACE527 Reduces the Incidence and Severity of Diarrhea in a Human Challenge Model of Diarrheal Disease
Michael J. Darsley, Subhra Chakraborty, Barbara DeNearing, David A. Sack, Andrea Feller, Charlotte Buchwaldt, A. Louis Bourgeois, Richard Walker, Clayton D. Harro
Clinical and Vaccine Immunology Nov 2012, 19 (12) 1921-1931; DOI: 10.1128/CVI.00364-12

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The Oral, Live Attenuated Enterotoxigenic Escherichia coli Vaccine ACE527 Reduces the Incidence and Severity of Diarrhea in a Human Challenge Model of Diarrheal Disease
Michael J. Darsley, Subhra Chakraborty, Barbara DeNearing, David A. Sack, Andrea Feller, Charlotte Buchwaldt, A. Louis Bourgeois, Richard Walker, Clayton D. Harro
Clinical and Vaccine Immunology Nov 2012, 19 (12) 1921-1931; DOI: 10.1128/CVI.00364-12
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