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VACCINE RESEARCH

Selection and Characterization of Murine Monoclonal Antibodies to Staphylococcus aureus Iron-Regulated Surface Determinant B with Functional Activity In Vitro and In Vivo

Martha Brown, Rose Kowalski, Julie Zorman, Xin-min Wang, Victoria Towne, Qinjian Zhao, Susan Secore, Adam C. Finnefrock, Tim Ebert, Greg Pancari, Kevin Isett, Yuhua Zhang, Annaliesa S. Anderson, Donna Montgomery, Leslie Cope, Tessie McNeely
Martha Brown
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Rose Kowalski
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Julie Zorman
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Xin-min Wang
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Victoria Towne
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Qinjian Zhao
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Susan Secore
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Adam C. Finnefrock
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Tim Ebert
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Greg Pancari
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Kevin Isett
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Yuhua Zhang
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Annaliesa S. Anderson
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Donna Montgomery
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Leslie Cope
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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Tessie McNeely
Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
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  • For correspondence: tessie_mcneely@merck.com
DOI: 10.1128/CVI.00085-09
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Article Information

DOI 
https://doi.org/10.1128/CVI.00085-09
PubMed 
19553551

Published By 
American Society for Microbiology Journals
History 
  • Received February 27, 2009
  • Returned for modification March 23, 2009
  • Accepted June 12, 2009
  • Published online July 29, 2009.

Copyright & Usage 
Copyright © 2009 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (June 24, 2009).
  • You are viewing the most recent version of this article.

Author Information

  1. Martha Brown,
  2. Rose Kowalski,
  3. Julie Zorman,
  4. Xin-min Wang,
  5. Victoria Towne,
  6. Qinjian Zhao,
  7. Susan Secore,
  8. Adam C. Finnefrock,
  9. Tim Ebert,
  10. Greg Pancari,
  11. Kevin Isett,
  12. Yuhua Zhang,
  13. Annaliesa S. Anderson‡,
  14. Donna Montgomery,
  15. Leslie Cope and
  16. Tessie McNeely*
  1. Merck Research Labs, Merck and Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486
  • ↵‡ Present address: Wyeth Research, 401 N. Middletown Road 205/3112, Pearl River, NY 10965.

  • ↵* Corresponding author. Mailing address: Merck and Co., Inc., WP26-253, West Point, PA 19486. Phone: (215) 652-6752. Fax: (215) 993-1540. E-mail: tessie_mcneely{at}merck.com
  • † Supplemental material for this article may be found at http://cvi.asm.org/ .

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Selection and Characterization of Murine Monoclonal Antibodies to Staphylococcus aureus Iron-Regulated Surface Determinant B with Functional Activity In Vitro and In Vivo
Martha Brown, Rose Kowalski, Julie Zorman, Xin-min Wang, Victoria Towne, Qinjian Zhao, Susan Secore, Adam C. Finnefrock, Tim Ebert, Greg Pancari, Kevin Isett, Yuhua Zhang, Annaliesa S. Anderson, Donna Montgomery, Leslie Cope, Tessie McNeely
Clinical and Vaccine Immunology Jul 2009, 16 (8) 1095-1104; DOI: 10.1128/CVI.00085-09

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Selection and Characterization of Murine Monoclonal Antibodies to Staphylococcus aureus Iron-Regulated Surface Determinant B with Functional Activity In Vitro and In Vivo
Martha Brown, Rose Kowalski, Julie Zorman, Xin-min Wang, Victoria Towne, Qinjian Zhao, Susan Secore, Adam C. Finnefrock, Tim Ebert, Greg Pancari, Kevin Isett, Yuhua Zhang, Annaliesa S. Anderson, Donna Montgomery, Leslie Cope, Tessie McNeely
Clinical and Vaccine Immunology Jul 2009, 16 (8) 1095-1104; DOI: 10.1128/CVI.00085-09
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KEYWORDS

Antibodies, Bacterial
Antibodies, Monoclonal
Cation Transport Proteins
Staphylococcal Infections
Staphylococcus aureus

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