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VACCINE RESEARCH

DNA Vaccination by Electroporation and Boosting with Recombinant Proteins Enhances the Efficacy of DNA Vaccines for Schistosomiasis Japonica

Yang Dai, Yinchang Zhu, Donald A. Harn, Xiaoting Wang, Jianxia Tang, Song Zhao, Fei Lu, Xiaohong Guan
Yang Dai
1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
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Yinchang Zhu
1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
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  • For correspondence: yczhu2006@yahoo.com.cn
Donald A. Harn
2Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts
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Xiaoting Wang
1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
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Jianxia Tang
1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
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Song Zhao
1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
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Fei Lu
1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
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Xiaohong Guan
3Key Laboratory of Antibody Technique, Ministry of Health, Nanjing Medical University, Nanjing 210029, China
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DOI: 10.1128/CVI.00231-09
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Article Information

DOI 
https://doi.org/10.1128/CVI.00231-09
PubMed 
19812258

Published By 
American Society for Microbiology Journals
History 
  • Received June 7, 2009
  • Returned for modification September 2, 2009
  • Accepted September 29, 2009
  • Published online November 30, 2009.

Copyright & Usage 
Copyright © 2009 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (October 07, 2009).
  • You are viewing the most recent version of this article.

Author Information

  1. Yang Dai1,
  2. Yinchang Zhu1*,
  3. Donald A. Harn2†,
  4. Xiaoting Wang1,
  5. Jianxia Tang1,
  6. Song Zhao1,
  7. Fei Lu1 and
  8. Xiaohong Guan3
  1. 1Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Provincial Key Laboratory on Molecular Biology of Parasites, and Jiangsu Provincial Key Subject on Parasitic Diseases, Wuxi 214064, China
  2. 2Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts
  3. 3Key Laboratory of Antibody Technique, Ministry of Health, Nanjing Medical University, Nanjing 210029, China
  • ↵* Corresponding author. Mailing address: Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Jiangsu Key Lab on Molecular Biology of Parasites, Meiyuan, Wuxi, Jiangsu Province 214064, People's Republic of China. Phone: 86 510 8551 7721. Fax: 86 510 8551 0263. E-mail: yczhu2006{at}yahoo.com.cn
  • ↵† Present address: Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA.

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DNA Vaccination by Electroporation and Boosting with Recombinant Proteins Enhances the Efficacy of DNA Vaccines for Schistosomiasis Japonica
Yang Dai, Yinchang Zhu, Donald A. Harn, Xiaoting Wang, Jianxia Tang, Song Zhao, Fei Lu, Xiaohong Guan
Clinical and Vaccine Immunology Nov 2009, 16 (12) 1796-1803; DOI: 10.1128/CVI.00231-09

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DNA Vaccination by Electroporation and Boosting with Recombinant Proteins Enhances the Efficacy of DNA Vaccines for Schistosomiasis Japonica
Yang Dai, Yinchang Zhu, Donald A. Harn, Xiaoting Wang, Jianxia Tang, Song Zhao, Fei Lu, Xiaohong Guan
Clinical and Vaccine Immunology Nov 2009, 16 (12) 1796-1803; DOI: 10.1128/CVI.00231-09
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KEYWORDS

Antigens, Helminth
Helminth Proteins
Membrane Proteins
Recombinant Proteins
Schistosoma japonicum
Schistosomiasis japonica
Vaccines, DNA

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