Article Figures & Data
Figures
- FIG. 1.
Sensitivities of the whole-cell Leptospira assays according to the number of days of illness. Mean sensitivity and 95% confidence intervals are shown for the MAT screening titer criterion of ≥1:100 (MT) and the EIE-IgM-Leptospirose (BM), Leptospira IgM ELISA (PB), Dri-Dot (DD), and Dip-S-Tick (DS) assays.
Tables
- TABLE 1.
Performance of four serologic assays for leptospirosis in subject groups from an urban center with highly endemic transmission in Brazil
Assaya % Sensitivity (95% CI) for group in: % Specificity (95% CI) (n = 80) Acute phase (n = 96) Acute phase (n = 72)b Convalescent phase (n = 50)c MAT 68.8 (58.4-77.6) 45.8 (34.2-57.9) 100.0 (91.1-100.0) 100.0 (94.3-100.0) ELISA BM 79.2 (69.4-86.5) 54.2 (42.1-65.8) 96.0 (85.1-99.3) 95.0 (87.0-98.4) ELISA PB 87.5 (78.8-93.1) 66.7 (54.5-77.1) 92.0 (79.9-97.4) 87.5 (77.8-93.5) DD 80.0 (70.3-87.2) 50.0 (37.9-62.1) 84.0 (70.3-92.4) 95.0 (87.0-98.4) DS 72.3 (62.0-80.8) 32.9 (22.4-45.2) 80.0 (65.9-89.5) 100.0 (94.2-100.0) ↵ a ELISA BM, EIE-IgM-Leptospirose(Bio-Manguinhos); ELISA PB, Leptospira IgM ELISA(PanBio); DS, Dip-S-Tick(PanBio); DD, LeptoTek Dri-Dot (bioMérieux); MAT, using a screening titer criterion of ≥1:100 in the microagglutination test.
↵ b The acute-phase group included twenty-nine acute-phase patients and an additional 43 randomly selected patients; sera were collected <7 days from the onset of illness. CI, confidence interval.
↵ c Convalescent-phase cases were randomly selected from the 96-acute-phase-patient group.
