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MICROBIAL IMMUNOLOGY

Selective Pressures of HLA Genotypes and Antiviral Therapy on Human Immunodeficiency Virus Type 1 Sequence Mutation at a Population Level

Golo Ahlenstiel, Kirsten Roomp, Martin Däumer, Jacob Nattermann, Martin Vogel, Jürgen K. Rockstroh, Niko Beerenwinkel, Rolf Kaiser, Hans-Dieter Nischalke, Tilman Sauerbruch, Thomas Lengauer, Ulrich Spengler, ; on behalf of the Kompetenznetz HIV/AIDS
Golo Ahlenstiel
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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Kirsten Roomp
2Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany
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Martin Däumer
3Institute of Virology, University of Cologne, 50935 Cologne, Germany
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Jacob Nattermann
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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Martin Vogel
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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Jürgen K. Rockstroh
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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Niko Beerenwinkel
4Department of Mathematics, University of California, Berkeley, California
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Rolf Kaiser
3Institute of Virology, University of Cologne, 50935 Cologne, Germany
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Hans-Dieter Nischalke
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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Tilman Sauerbruch
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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Thomas Lengauer
2Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany
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Ulrich Spengler
1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
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  • For correspondence: ulrich.spengler@ukb.uni-bonn.de
DOI: 10.1128/CVI.00169-07
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Article Information

DOI 
https://doi.org/10.1128/CVI.00169-07
PubMed 
17715334

Published By 
American Society for Microbiology Journals
History 
  • Received April 18, 2007
  • Returned for modification May 31, 2007
  • Accepted August 2, 2007
  • Published online October 8, 2007.

Copyright & Usage 
Copyright © 2007 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (August 22, 2007).
  • You are viewing the most recent version of this article.

Author Information

  1. Golo Ahlenstiel1†,
  2. Kirsten Roomp2†,
  3. Martin Däumer3,
  4. Jacob Nattermann1,
  5. Martin Vogel1,
  6. Jürgen K. Rockstroh1,
  7. Niko Beerenwinkel4,
  8. Rolf Kaiser3,
  9. Hans-Dieter Nischalke1,
  10. Tilman Sauerbruch1,
  11. Thomas Lengauer2,
  12. Ulrich Spengler1* and
  13. on behalf of the Kompetenznetz HIV/AIDS
  1. 1Department of Internal Medicine I, University of Bonn, 53105 Bonn, Germany
  2. 2Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, 66123 Saarbrücken, Germany
  3. 3Institute of Virology, University of Cologne, 50935 Cologne, Germany
  4. 4Department of Mathematics, University of California, Berkeley, California
  • ↵† Both authors contributed equally to this work.

  • ↵* Corresponding author. Mailing address: Medizinische Klinik 1, Universitätskliniken Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany. Phone: 49 228 2876789. Fax: 49 228 2879822. E-mail: ulrich.spengler{at}ukb.uni-bonn.de
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Selective Pressures of HLA Genotypes and Antiviral Therapy on Human Immunodeficiency Virus Type 1 Sequence Mutation at a Population Level
Golo Ahlenstiel, Kirsten Roomp, Martin Däumer, Jacob Nattermann, Martin Vogel, Jürgen K. Rockstroh, Niko Beerenwinkel, Rolf Kaiser, Hans-Dieter Nischalke, Tilman Sauerbruch, Thomas Lengauer, Ulrich Spengler on behalf of the Kompetenznetz HIV/AIDS
Clinical and Vaccine Immunology Oct 2007, 14 (10) 1266-1273; DOI: 10.1128/CVI.00169-07

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Selective Pressures of HLA Genotypes and Antiviral Therapy on Human Immunodeficiency Virus Type 1 Sequence Mutation at a Population Level
Golo Ahlenstiel, Kirsten Roomp, Martin Däumer, Jacob Nattermann, Martin Vogel, Jürgen K. Rockstroh, Niko Beerenwinkel, Rolf Kaiser, Hans-Dieter Nischalke, Tilman Sauerbruch, Thomas Lengauer, Ulrich Spengler on behalf of the Kompetenznetz HIV/AIDS
Clinical and Vaccine Immunology Oct 2007, 14 (10) 1266-1273; DOI: 10.1128/CVI.00169-07
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KEYWORDS

Anti-HIV Agents
HIV Reverse Transcriptase
HIV-1
HLA Antigens
Mutation
Selection, Genetic

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