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Clin. Vaccine Immunol. doi:10.1128/CVI.00368-06
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Galactoxylomannan does not Exhibit Cross-Reactivity in the Platelia Aspergillus EIA

Albert Einstein College of Medicine, 1300 Morris Park Avenue, Forchheimer 411, Bronx, NY 10461; MiraVista Diagnostics, Indianapolis, IN, USA; National Cancer Institute, Pediatric Oncology Branch, Immunocompromised Host Section, CRC, Rm 1W-5750, 10 Center Drive, Bethesda, MD 20892-1100; Laboratory Animal Sciences Program, SAIC-Frederick, Inc., Frederick, MD 21702

^* To whom correspondence should be addressed. Email: jwheat{at}miravistalabs.com.

	Abstract

Given the recent report of a false-positive result in the Platelia Aspergillus EIA in a patient with cryptococcosis and in yeast extracts and purified galactoxylomannan of Cryptococcus neoformans, we evaluated culture extracts, purified polysaccharides, clinical specimens, and specimens from animals following experimental infection. Our results revealed no cross reactions.

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