CVI Accepts, published online ahead of print on 14 May 2008

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Clin. Vaccine Immunol. doi:10.1128/CVI.00085-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Rapid and simple diagnosis of Chlamydophila pneumoniae pneumonia using an immunochromatographic test for the detection of immunoglobulin M antibodies

Naoyuki Miyashita^*, Kazunobu Ouchi, Fumio Kishi, Mitsuaki Tabuchi, Naoki Tsumura, Hisaichi Bannai, Satoshi Iwata, Toshihiro Tanaka, and Mikio Oka

Division of Respiratory Diseases, Department of Medicine, Department of Pediatrics, and Department of Molecular Genetics, Kawasaki Medical School, Okayama, Department of Pediatrics, Kurume University School of Medicine, Fukuoka, Department of Medical Technology, School of Health Science, Kyorin University, Tokyo, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; and Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Canada

^* To whom correspondence should be addressed. Email: nao{at}med.kawasaki-m.ac.jp.

To evaluate a newly developed immunochromatographic test (MySet) for detecting anti-C. pneumoniae–specific immunoglobulin (Ig) M antibodies, MySet was compared with two serological tests. The sensitivity and specificity of MySet were 100% and 92.9%, respectively. MySet is rapid and simple to use and is thought to be a useful tool for the selection of appropriate antibiotic therapy.