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Clinical and Vaccine Immunology, July 2009, p. 1091-1092, Vol. 16, No. 7
1071-412X/09/$08.00+0     doi:10.1128/CVI.00083-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Evaluation of Oral Fluid Enzyme Immunoassay for Confirmation of a Positive Rapid Human Immunodeficiency Virus Test Result{triangledown}

L. G. Wesolowski,1* T. Sanchez,1 D. A. MacKellar,1 B. M. Branson,1 S. F. Ethridge,1 N. Constantine,2 F. Ketema,2 and P. S. Sullivan1

Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC, Atlanta, Georgia,1 University of Maryland, School of Medicine, Baltimore, Maryland2

Received 18 February 2009/ Returned for modification 8 April 2009/ Accepted 11 May 2009

The CDC recommends that a reactive rapid human immunodeficiency virus (HIV) test be confirmed with an approved supplemental test; the performance of an intermediate enzyme immunoassay (EIA) is optional. In support of this recommendation, it was found that of 1,431 reactive rapid HIV test results, 2 (0.1%) had false-negative oral fluid Western blot results and both had false-negative EIA results.

* Corresponding author. Mailing address: 1600 Clifton Rd., NE, MS E-46, Atlanta, GA 30333. Phone: (404) 639-6007. Fax: (404) 639-8640. E-mail: lig7{at}cdc.gov

{triangledown} Published ahead of print on 20 May 2009.

Clinical and Vaccine Immunology, July 2009, p. 1091-1092, Vol. 16, No. 7
1071-412X/09/$08.00+0     doi:10.1128/CVI.00083-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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