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Clinical and Vaccine Immunology, January 2009, p. 132-133, Vol. 16, No. 1
1071-412X/09/$08.00+0     doi:10.1128/CVI.00310-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Cross-Reactivity of Paracoccidioides brasiliensis, Histoplasma capsulatum, and Cryptococcus Species in the Commercial Platelia Aspergillus Enzyme Immunoassay{triangledown}

Melissa O. Xavier,1 Alessandro C. Pasqualotto,1,2,3* Isabel Cristina E. Cardoso,4 and Luiz Carlos Severo1,3,4

Postgraduation Program in Pulmonary Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil,1 Infection Control Department, Santa Casa-Complexo Hospitalar, Porto Alegre, Brazil,2 Conselho Nacional de Desenvolvimento e Pesquisa (CNPq), Brasilia, Brazil,3 Mycology Laboratory, Santa Casa-Complexo Hospitalar, Porto Alegre, RS, Brazil4

Received 21 August 2008/ Returned for modification 3 November 2008/ Accepted 13 November 2008

Cross-reactivity in the Platelia Aspergillus enzyme immunoassay was evaluated using 120 sera from patients with paracoccidioidomycosis, histoplasmosis, and cryptococcosis. At a cutoff value of 0.5, positivity rates were 50%, 67%, and 50%, respectively. The implications for these findings are discussed.

* Corresponding author. Mailing address: Av Independência 75, Hospital Dom Vicente Scherer, Serviço de Controle de Infecção Hospitalar, Porto Alegre 90035-075, Brazil. Phone: 55 51 99951614. Fax: 55 51 32148629. E-mail: pasqualotto{at}santacasa.tche.br

{triangledown} Published ahead of print on 19 November 2008.

Clinical and Vaccine Immunology, January 2009, p. 132-133, Vol. 16, No. 1
1071-412X/09/$08.00+0     doi:10.1128/CVI.00310-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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