This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ngo, T. D.
Right arrow Articles by Quinn, T. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ngo, T. D.
Right arrow Articles by Quinn, T. C.

 Previous Article  |  Next Article 

Clinical and Vaccine Immunology, August 2008, p. 1301-1303, Vol. 15, No. 8
1071-412X/08/$08.00+0     doi:10.1128/CVI.00006-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Comparison of Three Commercial Immunoassays for Detection of Herpes Simplex Virus Type 2 Antibodies in Commercial Sex Workers in Yunnan Province, China{triangledown}

Thoai D. Ngo,1 Oliver Laeyendecker,1,2 Rhoda Ashley Morrow,3 Shenghan Lai,4 and Thomas C. Quinn1,2*

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland,1 Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland,2 Department of Laboratory Medicine, University of Washington, Seattle, Washington,3 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland4

Received 7 January 2008/ Returned for modification 30 March 2008/ Accepted 18 May 2008

Five hundred commercial sex workers in China were tested for herpes simplex virus type 2 by three immunoassays and Western blotting. Sensitivities for the Focus, Kalon, and Biokit assays were 86.7%, 82.3%, and 34.9%, respectively, and specificities were 91.8%, 94.2%, and 60.1%, respectively. The Focus assay performed optimally at an index of 1.5 (95.2% sensitivity and 93.4% specificity), and the Kalon assay performed optimally at an index of 1.2 (93.3% sensitivity and 95.2% specificity).

* Corresponding author. Mailing address: Department of Infectious Diseases, Johns Hopkins University School of Medicine, 1721 East Madison Street, Ross Building, Room 1159, Baltimore, MD 21205. Phone: (410) 955-3151. Fax: (410) 614-9775. E-mail: tquinn{at}jhmi.edu

{triangledown} Published ahead of print on 28 May 2008.

Clinical and Vaccine Immunology, August 2008, p. 1301-1303, Vol. 15, No. 8
1071-412X/08/$08.00+0     doi:10.1128/CVI.00006-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»