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Clinical and Vaccine Immunology, June 2007, p. 802-803, Vol. 14, No. 6
1071-412X/07/$08.00+0     doi:10.1128/CVI.00035-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Evaluation of the IMMY ALPHA Histoplasma Antigen Enzyme Immunoassay for Diagnosis of Histoplasmosis Marked by Antigenuria{triangledown}

Ann LeMonte,* Lindsey Egan, Patricia Connolly, Michelle Durkin, and L. Joseph Wheat

MiraVista Diagnostics and MiraBella Technologies, Indianapolis, Indiana

Received 16 January 2007/ Returned for modification 8 March 2007/ Accepted 22 March 2007

The sensitivity of detection of antigenuria in patients positive by the MiraVista Diagnostics Histoplasma enzyme immunoassay (MVD EIA) was 44% with the IMMY ALPHA Histoplasma antigen EIA. The specificity was 84% with the IMMY EIA versus 98% with the MVD EIA. The correlation between assays for positive cases was weak (r2 = 0.430).


* Corresponding author. Mailing address: MiraVista Diagnostics, 4444 Decatur Blvd., Indianapolis, IN 46241. Phone: (317) 856-2681, ext. 459. Fax: (317) 856-3685. E-mail: alemonte{at}miravistalabs.com

{triangledown} Published ahead of print on 4 April 2007.


Clinical and Vaccine Immunology, June 2007, p. 802-803, Vol. 14, No. 6
1071-412X/07/$08.00+0     doi:10.1128/CVI.00035-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:

  • Cloud, J. L., Bauman, S. K., Pelfrey, J. M., Ashwood, E. R., Wheat, L. J., LeMonte, A. (2007). Biased Report on the IMMY ALPHA Histoplasma Antigen Enzyme Immunoassay for Diagnosis of Histoplasmosis. CVI 14: 1389-1391 [Full Text]