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Clinical and Vaccine Immunology, December 2007, p. 1640-1643, Vol. 14, No. 12
1071-412X/07/$08.00+0     doi:10.1128/CVI.00251-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Dense-Granule Protein NcGRA7, a New Marker for the Serodiagnosis of Neospora caninum Infection in Aborting Cows{triangledown}

Penglong Huang, Min Liao, Houshuang Zhang, Eung-goo Lee, Yoshifumi Nishikawa,* and Xuenan Xuan

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan

Received 18 June 2007/ Returned for modification 3 October 2007/ Accepted 16 October 2007

To investigate whether the production of an antigen-specific antibody is associated with Neospora caninum-induced bovine abortion, 62 serum samples were tested with an enzyme-linked immunosorbent assay using the recombinant antigens NcSAG1, NcSRS2, and NcGRA7. Our study suggested that NcGRA7 would be a new marker for the serodiagnosis of N. caninum infection resulting in abortion.

* Corresponding author. Mailing address: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan. Phone: 81-155-49-5886. Fax: 81-155-49-5643. E-mail: nisikawa{at}obihiro.ac.jp

{triangledown} Published ahead of print on 24 October 2007.

Clinical and Vaccine Immunology, December 2007, p. 1640-1643, Vol. 14, No. 12
1071-412X/07/$08.00+0     doi:10.1128/CVI.00251-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Nishikawa, Y., Zhang, H., Ikehara, Y., Kojima, N., Xuan, X., Yokoyama, N. (2009). Immunization with Oligomannose-Coated Liposome-Entrapped Dense Granule Protein 7 Protects Dams and Offspring from Neospora caninum Infection in Mice. CVI 16: 792-797 [Abstract] [Full Text]  
  • Baszler, T. V., Shkap, V., Mwangi, W., Davies, C. J., Mathison, B. A., Mazuz, M., Resnikov, D., Fish, L., Leibovitch, B., Staska, L. M., Savitsky, I. (2008). Bovine Immune Response to Inoculation with Neospora caninum Surface Antigen SRS2 Lipopeptides Mimics Immune Response to Infection with Live Parasites. CVI 15: 659-667 [Abstract] [Full Text]  


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