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Clinical and Vaccine Immunology, October 2007, p. 1370-1371, Vol. 14, No. 10
1071-412X/07/$08.00+0     doi:10.1128/CVI.00246-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Persistence of Antibodies Induced by Measles-Mumps-Rubella Vaccine in Children in India{triangledown}

S. K. Raut,1 P. S. Kulkarni,1* M. A. Phadke,2 S. S. Jadhav,1 S. V. Kapre,1 R. M. Dhere,1 S. P. Dhorje,1 and S. R. Godse1

Serum Institute of India Ltd., Pune,1 Maharashtra University of Health Sciences, Nasik, India2

Received 15 June 2007/ Returned for modification 27 June 2007/ Accepted 6 August 2007

Antibody levels in 41 Indian girls were measured 6 years after measles-mumps-rubella (MMR) vaccination. Rates of seropositivity were 88% (measles antibodies), 95% (mumps antibodies), and 100% (rubella antibodies). The MMR vaccine induces long-term immunity in a majority of vaccinees; however, due to the observation of some seronegative vaccinees, the policy of administering a second dose of the MMR vaccine seems appropriate.

* Corresponding author. Mailing address: Serum Institute of India Ltd., Pune, 212/2, Hadapsar, Pune-411028, India. Phone: 91-20-26602384. Fax: 91-20-26993945. E-mail: drpsk{at}seruminstitute.com

{triangledown} Published ahead of print on 15 August 2007.

Clinical and Vaccine Immunology, October 2007, p. 1370-1371, Vol. 14, No. 10
1071-412X/07/$08.00+0     doi:10.1128/CVI.00246-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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