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Clinical and Vaccine Immunology, January 2007, p. 85-86, Vol. 14, No. 1
1071-412X/07/$08.00+0     doi:10.1128/CVI.00253-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Dynamics of Helicobacter pylori-Specific Immunoglobulin G for 2 Years after Successful Eradication of Helicobacter pylori Infection in an American Indian and Alaska Native Population{triangledown}

Karen M. Miernyk,1* Dana L. Bruden,2 Michael G. Bruce,2 Brian J. McMahon,1 Thomas W. Hennessy,2 Helen V. Peters,1 Debby A. Hurlburt,2 Frank Sacco,3 and Alan J. Parkinson2

Alaska Native Tribal Health Consortium,1 Arctic Investigations Program, Centers for Disease Control and Prevention,2 Alaska Native Medical Center, Anchorage, Alaska3

Received 10 July 2006/ Returned for modification 11 August 2006/ Accepted 23 October 2006

Helicobacter pylori antibodies were measured over 24 months in American Indian and Alaska Native persons who cleared their infections. Two months after treatment, 82% of H. pylori-negative persons remained seropositive. While there were declines in H. pylori antibodies for 12 months, after 24 months 71% of persons remained seropositive.

* Corresponding author. Mailing address: Arctic Investigations Program, Centers for Disease Control and Prevention, 4055 Tudor Centre Dr., Anchorage, AK 99508. Phone: (907) 729-3453. Fax: (907) 729-3429. E-mail: kmiernyk{at}cdc.gov.

{triangledown} Published ahead of print on 1 November 2006.

Clinical and Vaccine Immunology, January 2007, p. 85-86, Vol. 14, No. 1
1071-412X/07/$08.00+0     doi:10.1128/CVI.00253-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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