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 Previous Article

Clinical and Vaccine Immunology, July 2006, p. 818-819, Vol. 13, No. 7
1071-412X/06/$08.00+0     doi:10.1128/CVI.00025-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Toll-Like Receptor 2 Polymorphisms and Nontuberculous Mycobacterial Lung Diseases

Yon Ju Ryu ,1,{dagger},{ddagger} Eun Joo Kim,1,{ddagger} Won-Jung Koh,1* Hojoong Kim,1 O Jung Kwon,1 and Jung Hyun Chang2

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine,1 Department of Internal Medicine, Ewha Womans University, College of Medicine, Seoul, Korea2

Received 21 January 2006/ Returned for modification 14 April 2006/ Accepted 17 May 2006

To investigate the occurrence of the Toll-like receptor 2 (TLR2) polymorphisms in patients with pulmonary disease caused by nontuberculous mycobacteria (NTM), TLR2 Arg677Trp and Arg753Gln polymorphisms were examined. TLR2 polymorphisms do not appear to be responsible for host susceptibility to NTM lung disease, at least in the Korean population.

* Corresponding author. Mailing address: Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Korea. Phone: 82 2 3410 3429. Fax: 82 2 3410 3849. E-mail: wjkoh{at}smc.samsung.co.kr.

{dagger} Present address: Department of Internal Medicine, Dongdaemun Hospital, Ewha Womans University, College of Medicine, Jongno 6-ga, Jongno-gu, Seoul 110-783, Korea.

{ddagger} Y.J.R. and E.J.K. contributed equally as joint first authors.

Clinical and Vaccine Immunology, July 2006, p. 818-819, Vol. 13, No. 7
1071-412X/06/$08.00+0     doi:10.1128/CVI.00025-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Ryu, Y. J., Kim, E. J., Lee, S-H., Kim, S. Y., Suh, G. Y., Chung, M. P., Kim, H., Kwon, O. J., Koh, W-J. (2007). Impaired expression of Toll-like receptor 2 in nontuberculous mycobacterial lung disease. Eur Respir J 30: 736-742 [Abstract] [Full Text]  


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