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Clinical and Vaccine Immunology, October 2006, p. 1175-1176, Vol. 13, No. 10
1071-412X/06/$08.00+0     doi:10.1128/CVI.00197-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

High Levels of Serum Thromboxane B2 Are Generated during Human Pulmonary Dirofilariosis

R. Morchón,1 J. López-Belmonte,1 A. Rodríguez-Barbero,2 and F. Simón1*

Laboratorio de Parasitología, Facultad de Farmacia, Universidad de Salamanca, Avda. Campo Charro s/n 37007 Salamanca, Spain,1 Instituto Reina Sofia de Investigación Nefrológica, Departamento de Fisiología y Farmacología, Universidad de Salamanca, Campus Miguel de Unamuno 37007, Salamanca, Spain2

Received 31 May 2006/ Returned for modification 7 July 2006/ Accepted 26 July 2006

The canine parasite Dirofilaria immitis can infect humans. Patients with pulmonary dirofilariosis develop significantly higher thromboxane B2 levels than healthy individuals living in areas where dirofilariosis is endemic and in areas where dirofilariosis is not endemic. The possible role of Wolbachia bacteria in the appearance of this eicosanoid is discussed.

* Corresponding author. Mailing address: Laboratorio de Parasitología, Facultad de Farmacia, Universidad de Salamanca, Avda. Campo Charro s/n, 37007, Salamanca, Spain. Phone: 34 923 294535. Fax: 34 923 294515. E-mail: fersimon{at}usal.es.

Clinical and Vaccine Immunology, October 2006, p. 1175-1176, Vol. 13, No. 10
1071-412X/06/$08.00+0     doi:10.1128/CVI.00197-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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