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Clinical and Vaccine Immunology, January 2006, p. 150-151, Vol. 13, No. 1
1071-412X/06/$08.00+0     doi:10.1128/CVI.13.1.150-151.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Evaluation of the INOVA Diagnostics Enzyme-Linked Immunosorbent Assay Kits for Measuring Serum Immunoglobulin G (IgG) and IgA to Deamidated Gliadin Peptides

Focus Diagnostics, Cypress, California 90630

Received 9 September 2005/ Accepted 18 October 2005

New assays for antibodies to deamidated gliadin peptides (DGP) expressing celiac disease-specific epitopes were evaluated using 154 sera previously tested for endomysial immunoglobulin A (IgA) (EMA), transglutaminase IgA (TGA), and conventional gliadin antibodies. DGP antibody results showed 97% concordance with EMA and TGA results. Of 56 sera negative for EMA and TGA but positive for conventional gliadin antibodies, 54 (96%) were negative for DGP antibodies.