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Clinical and Diagnostic Laboratory Immunology, February 2005, p. 359-360, Vol. 12, No. 2
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.2.359-360.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Performance of Two Commercial Enzyme-Linked Immunosorbent Assay Kits Using Recombinant Glycoprotein G2 Antigen for Detection of Herpes Simplex Virus Type 2 Specific Antibodies

Sharmila M. Reddy,1 P. Balakrishnan,1* S. Uma,1 S. P. Thyagarajan,2 and Suniti Solomon1

YRG CARE, Centre for AIDS Research and Education,1 University of Madras, Chennai, India2

Received 22 July 2004/ Returned for modification 15 September 2004/ Accepted 17 November 2004

For 93 stored serum samples tested by HerpeSelect2 and the Euroimmun enzyme-linked immunosorbent assay for detection of herpes simplex virus type 2-specific immunoglobulin G antibodies, the concordance of positive and negative results was 100%. Moreover, all the results that were equivocal by HerpeSelect2 (negative by Euroimmun) were confirmed as being negative by a Western blot assay.

* Corresponding author. Mailing address: YRG CARE, Centre for AIDS Research and Education, VHS, Taramani, Chennai 600 113, India. Phone: 91-44-22542929. Fax: 91-44-22542939. E-mail: bala{at}yrgcare.org.

Clinical and Diagnostic Laboratory Immunology, February 2005, p. 359-360, Vol. 12, No. 2
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.2.359-360.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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