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Clinical and Diagnostic Laboratory Immunology, October 2005, p. 1243-1245, Vol. 12, No. 10
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.10.1243-1245.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Immunogenicity of an Intranasally Administered Modified Live Canine Parvovirus Type 2b Vaccine in Pups with Maternally Derived Antibodies

Vito Martella,* Alessandra Cavalli, Nicola Decaro, Gabriella Elia, Costantina Desario, Marco Campolo, Giancarlo Bozzo, Elvira Tarsitano, and Canio Buonavoglia

Department of Animal Health and Well-Being, Faculty of Veterinary Medicine, University of Bari, S.p. per Casamassima km 3, 70010 Valenzano, Bari, Italy

Received 17 May 2005/ Returned for modification 11 July 2005/ Accepted 19 July 2005

The ability of a modified live canine parvovirus type 2b vaccine to elicit active immunization in pups with maternally derived antibodies (MDA) by intranasal administration was evaluated. The vaccine induced seroconversion in 100% of pups with MDA titers of ≤80 and in 51.6% of pups with titers between 160 and 320.

* Corresponding author. Mailing address: Dipartimento di Sanità e Benessere Animale, Facoltà di Medicina Veterinaria, Università di Bari, S.p. per Casamassima km 3, 70010 Valenzano, Bari, Italy. Phone: 39 080 4679805. Fax: 39 080 4679043. E-mail: v.martella{at}veterinaria.uniba.it.

Clinical and Diagnostic Laboratory Immunology, October 2005, p. 1243-1245, Vol. 12, No. 10
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.10.1243-1245.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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Copyright © 2005 by the American Society for Microbiology. All rights reserved.