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 Previous Article

Clinical and Diagnostic Laboratory Immunology, January 2005, p. 231-233, Vol. 12, No. 1
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.1.231-233.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Evaluation of a West Nile Virus Immunoglobulin A Capture Enzyme-Linked Immunosorbent Assay

Harry E. Prince* and Mary Lapé-Nixon

Focus Technologies, Cypress, California

Received 20 August 2004/ Returned for modification 27 September 2004/ Accepted 30 September 2004

An in-house-developed enzyme-linked immunosorbent assay detected West Nile virus (WNV) immunoglobulin A (IgA) in 65 of 68 sera from WNV-infected patients; 40 of 63 WNV IgM-positive, IgG-negative serum or plasma specimens; 65 of 67 WNV IgM-positive, IgG-positive specimens; 0 of 70 WNV IgM-negative, IgG-negative specimens; and 0 of 64 archived blood donation sera. WNV IgA is thus highly prevalent among WNV-infected patients and typically appears after WNV IgM but before WNV IgG.

* Corresponding author. Mailing address: 5785 Corporate Ave., Cypress, CA 90630. Phone: (714) 503-2047. Fax: (714) 484-1296. E-mail: hprince{at}focustechnologies.com.

Clinical and Diagnostic Laboratory Immunology, January 2005, p. 231-233, Vol. 12, No. 1
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.1.231-233.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Levett, P. N., Sonnenberg, K., Sidaway, F., Shead, S., Niedrig, M., Steinhagen, K., Horsman, G. B., Drebot, M. A. (2005). Use of Immunoglobulin G Avidity Assays for Differentiation of Primary from Previous Infections with West Nile Virus. J. Clin. Microbiol. 43: 5873-5875 [Abstract] [Full Text]  
  • Prince, H. E., Tobler, L. H., Lape-Nixon, M., Foster, G. A., Stramer, S. L., Busch, M. P. (2005). Development and Persistence of West Nile Virus-Specific Immunoglobulin M (IgM), IgA, and IgG in Viremic Blood Donors. J. Clin. Microbiol. 43: 4316-4320 [Abstract] [Full Text]  


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